CCDC141 Synthetic Peptide, PEP-1283, from Invitrogen.
Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-175460 |
| Réf. fabricant | 15205289 |
| Gene ID (Entrez) | 285025 |
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| Espèces | Human |
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| Méthode de purification | purified |
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| Numéro d’adhésion | Q6ZP82 |
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| Nom usuel | Human CCDC141 |
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| Concentration | 200 μg/mL |
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| Contenu et stockage | -20°C |
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| Format | Liquid |
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| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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| À utiliser avec (application) | Blocking Assay, Control |
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| Symbole de gène(s) | CCDC141 |
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| Lyophilisé | No |
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| Conservateur | 0.02% sodium azide |
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| Type de produit | Peptide |
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| Quantité | 50 μg |
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| État réglementaire | RUO - research use only |
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| Tampon de stockage | PBS |
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