Synthetic Peptide
Human BACE2 (residues 503-518) Synthetic Peptide, PEP-167, from Invitrogen.
BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-175639 |
| Réf. fabricant | 11574820 |
| Gene ID (Entrez) | 25825 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q9Y5Z0 |
| Nom usuel | Human BACE2 (aa 503-518) |
| Concentration | 0.5 mg/mL |
| Contenu et stockage | -20°C. Avoid freeze-thaw cycles. |
| Format | Lyophilized |
| Formule | peptide with no preservative |
| À utiliser avec (application) | Control |
| Symbole de gène(s) | BACE2 |
| Lyophilisé | Lyophilized |
| Conservateur | No preservative |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Séquence | C-P(503)-E-V-V-N-D-E-S-S-L-V-R-H-R-W-K(518) |
