Synthetic Peptide
TCIRG1 Synthetic Peptide, PEP-1461, from Invitrogen.
The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-175775 |
| Réf. fabricant | 15265369 |
| Gene ID (Entrez) | 10312 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q13488 |
| Nom usuel | Human TCIRG1 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| À utiliser avec (application) | Blocking Assay, Control |
| Symbole de gène(s) | TCIRG1 |
| Lyophilisé | No |
| Conservateur | 0.02% sodium azide |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Tampon de stockage | PBS |
