N4BP1 Synthetic Peptide, PEP-1213, from Invitrogen.
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-175920 |
| Réf. fabricant | 15205219 |
| Gene ID (Entrez) | 9683 |
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| Espèces | Human |
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| Méthode de purification | purified |
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| Numéro d’adhésion | O75113 |
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| Nom usuel | Human N4BP1 |
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| Concentration | 200 μg/mL |
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| Contenu et stockage | -20°C |
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| Format | Liquid |
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| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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| À utiliser avec (application) | Blocking Assay, Control |
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| Symbole de gène(s) | N4BP1 |
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| Lyophilisé | No |
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| Conservateur | 0.02% sodium azide |
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| Type de produit | Peptide |
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| Quantité | 50 μg |
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| État réglementaire | RUO - research use only |
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| Tampon de stockage | PBS |
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