Synthetic Peptide
APH1 Synthetic Peptide, PEP-0438, from Invitrogen.
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176057 |
| Réf. fabricant | 15256649 |
| Gene ID (Entrez) | 51107 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q96BI3 |
| Nom usuel | Human APH1 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| À utiliser avec (application) | Blocking Assay, Control |
| Symbole de gène(s) | APH1A |
| Lyophilisé | No |
| Conservateur | 0.02% sodium azide |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Tampon de stockage | PBS |
