Synthetic Peptide
Human 20S Proteasome Z (residues 263-277) Synthetic Peptide, PEP-175, from Invitrogen.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176084 |
| Réf. fabricant | 11554830 |
| Gene ID (Entrez) | 5695 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q99436 |
| Nom usuel | Human 20 S Proteasome Z (aa 263-277) |
| Concentration | 0.5 mg/mL |
| Contenu et stockage | -20°C. Avoid freeze-thaw cycles. |
| Format | Lyophilized |
| Formule | peptide with no preservative |
| À utiliser avec (application) | Control |
| Symbole de gène(s) | PSMB7 |
| Lyophilisé | Lyophilized |
| Conservateur | No preservative |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Séquence | C-E(263)-I-E-V-L-E-E-T-V-Q-T-M-D-T-S(NH2)(277) |
