Synthetic Peptide
BACE2 Synthetic Peptide, PEP-0075, from Invitrogen.
BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176437 |
| Réf. fabricant | 15256299 |
| Gene ID (Entrez) | 25825 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q9Y5Z0 |
| Nom usuel | Human BACE2 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| À utiliser avec (application) | Blocking Assay, Control |
| Symbole de gène(s) | BACE2 |
| Lyophilisé | No |
| Conservateur | 0.02% sodium azide |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Tampon de stockage | PBS |
