Synthetic Peptide
TMEM59 Synthetic Peptide, PEP-1179, from Invitrogen.
Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176443 |
| Réf. fabricant | 15275179 |
| Gene ID (Entrez) | 9528 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q9BXS4 |
| Nom usuel | Human TMEM59 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| À utiliser avec (application) | Blocking Assay, Control |
| Symbole de gène(s) | TMEM59 |
| Lyophilisé | No |
| Conservateur | 0.02% sodium azide |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Tampon de stockage | PBS |
