Synthetic Peptide
TMEM88 Synthetic Peptide, PEP-1278, from Invitrogen.
Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176550 |
| Réf. fabricant | 15255279 |
| Gene ID (Entrez) | 92162 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q6PEY1 |
| Nom usuel | Human TMEM88 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| À utiliser avec (application) | Blocking Assay, Control |
| Symbole de gène(s) | TMEM88 |
| Lyophilisé | No |
| Conservateur | 0.02% sodium azide |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Tampon de stockage | PBS |
