DR4 Synthetic Peptide, PEP-0011, from Invitrogen.
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-176561 |
| Réf. fabricant | 15236239 |
| Gene ID (Entrez) | 8797 |
|---|
| Espèces | Human |
|---|
| Méthode de purification | purified |
|---|
| Numéro d’adhésion | O00220 |
|---|
| Nom usuel | Human DR4 |
|---|
| Concentration | 200 μg/mL |
|---|
| Contenu et stockage | -20°C |
|---|
| Format | Liquid |
|---|
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
|---|
| À utiliser avec (application) | Blocking Assay, Control |
|---|
| Symbole de gène(s) | TNFRSF10A |
|---|
| Lyophilisé | No |
|---|
| Conservateur | 0.02% sodium azide |
|---|
| Type de produit | Peptide |
|---|
| Quantité | 50 μg |
|---|
| État réglementaire | RUO - research use only |
|---|
| Tampon de stockage | PBS |
Une question, une configuration particulière ?
Contactez-nous pour un devis.