TRESK Synthetic Peptide, PEP-0987, from Invitrogen.
TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-176703 |
| Réf. fabricant | 15379240 |
| Gene ID (Entrez) | 338567 |
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| Espèces | Human |
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| Méthode de purification | purified |
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| Numéro d’adhésion | Q7Z418 |
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| Nom usuel | Human KCNK18 |
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| Concentration | 200 μg/mL |
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| Contenu et stockage | -20°C |
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| Format | Liquid |
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| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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| À utiliser avec (application) | Blocking Assay, Control |
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| Symbole de gène(s) | KCNK18 |
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| Lyophilisé | No |
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| Conservateur | 0.02% sodium azide |
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| Type de produit | Peptide |
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| Quantité | 50 μg |
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| État réglementaire | RUO - research use only |
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| Tampon de stockage | PBS |
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