NALP10 Synthetic Peptide, PEP-1139, from Invitrogen.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1-b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1-b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-176712 |
| Réf. fabricant | 15275139 |
| Gene ID (Entrez) | 338322 |
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| Espèces | Human |
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| Méthode de purification | purified |
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| Numéro d’adhésion | Q86W26 |
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| Nom usuel | Human NALP10 |
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| Concentration | 200 μg/mL |
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| Contenu et stockage | -20°C |
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| Format | Liquid |
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| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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| À utiliser avec (application) | Blocking Assay, Control |
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| Symbole de gène(s) | NLRP10 |
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| Lyophilisé | No |
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| Conservateur | 0.02% sodium azide |
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| Type de produit | Peptide |
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| Quantité | 50 μg |
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| État réglementaire | RUO - research use only |
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| Tampon de stockage | PBS |
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