Synthetic Peptide
CRIM2 Synthetic Peptide, PEP-1453, from Invitrogen.
CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-Beta1, suppressing activin- and TGF-Beta1-dependent transcription.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176738 |
| Réf. fabricant | 15285359 |
| Gene ID (Entrez) | 375616 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | Q6ZWJ8 |
| Nom usuel | Human CRIM2 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| À utiliser avec (application) | Blocking Assay, Control |
| Symbole de gène(s) | KCP |
| Lyophilisé | No |
| Conservateur | 0.02% sodium azide |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Tampon de stockage | PBS |
