Synthetic Peptide
Hyuman S1P1 (residues 359-372) Synthetic Peptide, PEP-220, from Invitrogen.
S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-176838 |
| Réf. fabricant | 11514870 |
| Gene ID (Entrez) | 1901 |
| Espèces | Mouse |
| Méthode de purification | purified |
| Numéro d’adhésion | P21453 |
| Nom usuel | Human S1P1 (aa 359-372) |
| Concentration | 0.5 mg/mL |
| Contenu et stockage | -20°C. Avoid freeze-thaw cycles. |
| Format | Lyophilized |
| Formule | peptide with no preservative |
| À utiliser avec (application) | Control |
| Symbole de gène(s) | S1PR1 |
| Lyophilisé | Lyophilized |
| Conservateur | No preservative |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Séquence | SHPQKDDGDN PETI |
