Human Kinesin 5B (residues 376-396) Synthetic Peptide, PEP-198, from Invitrogen.
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-176871 |
| Réf. fabricant | 11564850 |
| Gene ID (Entrez) | 3799 |
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| Espèces | Human |
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| Méthode de purification | purified |
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| Numéro d’adhésion | P33176 |
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| Nom usuel | Human Kinesin 5 B (aa 376-396) |
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| Concentration | 0.5 mg/mL |
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| Contenu et stockage | -20°C. Avoid freeze-thaw cycles. |
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| Format | Lyophilized |
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| Formule | peptide with no preservative |
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| À utiliser avec (application) | Control |
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| Symbole de gène(s) | KIF5B |
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| Lyophilisé | Lyophilized |
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| Conservateur | No preservative |
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| Type de produit | Peptide |
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| Quantité | 50 μg |
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| État réglementaire | RUO - research use only |
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| Séquence | C I D E Q F D K E K A N L E A F T V D K D I |
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