N-RAS Synthetic Peptide, PEP-1603, from Invitrogen.
NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-176885 |
| Réf. fabricant | 15265529 |
| Gene ID (Entrez) | 4893 |
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| Espèces | Human |
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| Méthode de purification | purified |
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| Numéro d’adhésion | P01111 |
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| Nom usuel | Human N-Ras |
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| Concentration | 200 μg/mL |
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| Contenu et stockage | -20°C |
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| Format | Liquid |
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| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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| À utiliser avec (application) | Blocking Assay, Control |
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| Alias de gène | N-RAS, Neuroblastoma RAS, NRAS, NRAS1, NS6, ALPS4, Neuroblastoma RAS viral (v-ras) oncogene homolog, RAS, RASN, GTPase Nras, Transforming protein N-Ras |
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| Symbole de gène(s) | NRAS |
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| Lyophilisé | No |
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| Conservateur | 0.02% sodium azide |
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| Type de produit | Peptide |
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| Quantité | 50 μg |
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| État réglementaire | RUO - research use only |
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| Tampon de stockage | PBS |
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