Synthetic Peptide
Rat VAMP-2 (residues 1-18) Synthetic Peptide, PEP-101, from Invitrogen.
The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-177110 |
| Réf. fabricant | 11564750 |
| Gene ID (Entrez) | 24803 |
| Espèces | Rat |
| Méthode de purification | purified |
| Numéro d’adhésion | P63045 |
| Nom usuel | Rat VAMP2 (aa 1-18) |
| Concentration | 0.5 mg/mL |
| Contenu et stockage | -20°C. Avoid freeze-thaw cycles. |
| Format | Lyophilized |
| Formule | peptide with no preservative |
| À utiliser avec (application) | Control |
| Symbole de gène(s) | Vamp2 |
| Lyophilisé | Lyophilized |
| Conservateur | No preservative |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Séquence | M(1)-S-A-T-A-A-T-V-P-P-A-A-P-A-G-E-G-G(18) |
