Synthetic Peptide
Human HDAC4 (residues 1071-1084) Synthetic Peptide, PEP-141, from Invitrogen.
Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-177154 |
| Réf. fabricant | 11524800 |
| Gene ID (Entrez) | 9759 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d’adhésion | P56524 |
| Nom usuel | Human HDAC4 (aa 1071-1084) |
| Concentration | 0.5 mg/mL |
| Contenu et stockage | -20°C. Avoid freeze-thaw cycles. |
| Format | Lyophilized |
| Formule | peptide with no preservative |
| À utiliser avec (application) | Control |
| Symbole de gène(s) | HDAC4 |
| Lyophilisé | Lyophilized |
| Conservateur | No preservative |
| Type de produit | Peptide |
| Quantité | 50 μg |
| État réglementaire | RUO - research use only |
| Séquence | K(1071)-R-P-D-E-E-P-M-E-E-E-P-P-L(1084) |
