Native Protein
RP-43142 contains native human Fibrinogen protein. RP-43142 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-177384 |
| Réf. fabricant | 11534171 |
| Numéro d’adhésion | P02671, P02675, P02679 |
| Concentration | 4.3 mg/mL |
| À utiliser avec (application) | Control |
| Formule | 0.01 M sodium citrate, 0.01 M sodium phosphate with no preservative; pH 7.3 |
| Identification génétique (Entrez) | 2243, 2244, 2266 |
| Poids moléculaire | 340 kDa |
| Nom | Human Fibrinogen |
| Plage de pH | 7.3 |
| Quantité | 2 mg |
| Source | Human |
| État réglementaire | RUO |
| Alias de gène | 2510049G14Rik; 3010002H13Rik; A-alpha fibrinogen; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; carboxy-terminal region; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78 p; Fba5e; Fga; Fgb; Fgg; Fib; Fib2; fibg; fibrinogen; fibrinogen A-alpha chain; fibrinogen A-alpha-chain; fibrinogen alpha chain; fibrinogen alpha-E subunit; fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma polypeptide; fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; Gamma'; gamma-fibrinogen; HEL-S-78 p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951) |
| Nom usuel | Fibrinogen |
| Symbole de gène(s) | FGA |
| Conjugué | Unconjugated |
| Espèces | Human |
| Contenu et stockage | -80°C, Avoid Freeze/Thaw Cycles |
| Forme | Liquid |
| Sous-type de protéine | Native |
