"/> Tocris Bioscience™ MS 4322 | B-LABO France

Tocris Bioscience™ MS 4322

Name: Tocris Bioscience™ MS 4322
Brand: Tocris Bioscience
SKU: 30279884
Price: 348.80 EUR
Availability: InStock

Réf. : BL-RE-177673Réf. fabricant : 30279884

348,80 € HT

Selective PRMT5 Degrader (PROTAC™)

Marque: Tocris Bioscience

MS 4322 is a protein arginine methyltransferase 5 (PRMT5) Degrader (PROTAC™) (DC50 = 1.1 μM, Dmax = 74% in MCF-7 cells). Also inhibits PRMT5 methyltransferase activity (IC50 = 18 nM) and dose-dependently inhibits proliferation of HeLa, A549, A172 and Jurkat cancer cell lines. Comprises a PRMT5 inhibitor linked to an E3 ligase ligand.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.