Tocris Bioscience™ MPD 2
412,52 € HT
SARS-CoV-2 Mpro Degrader (PROTAC™)
- Marque
- Tocris Bioscience
MPD 2 is a SARS-CoV-2 Mpro Degrader (PROTAC™) (DC50 = 296 nM in 293T cells). Mpro degradation is time-dependent and CRBN-mediated. Antiviral in A549-ACE2 cells infected with several SARS-CoV-2 strains (EC50 = 492 nM at delta variant) and against a nirmatrelvir-resistant mutant of SARS-CoV-2, NSP5 E166A (EC50 = 460 nM).
PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.
Caractéristiques techniques
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-177676 |
| Réf. fabricant | 30279879 |
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