ELISA
ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-177860 |
| Réf. fabricant | 30245384 |
| Numéro d’adhésion | P12724 |
| Plage de dosage | 39.06 to 2500 pg/mL |
| Sensibilité du dosage | 23.44 pg/mL |
| Conjugué | HRP |
| Type de produit | ELISA |
| Type d’échantillon | Plasma, Serum |
| À utiliser avec (équipement) | Colorimetric Microplate Reader |
| Identification génétique (Entrez) | 6037 |
| Symbole de gène(s) | RNASE3 |
| Coefficient de variation inter-dosage | <10 |
| Coefficient de variation intra-dosage | <10 |
| Contenus des kits | Micro ELISA Plate (Dismountable), Reference Standard, Concentrated Biotinylated Detection Ab(100x), Concentrated HRP Conjugate (100x), Reference Standard & Sample Diluent, Biotinylated Detection Ab Diluent, HRP Conjugate Diluent, Concentrated Wash Buffer(25x), Substrate Reagent, Stop Solution, Plate Sealer, Product Description, Certificate of Analysis |
| Marqueur ou colorant | Biotin |
| Quantité | 96 Tests |
| État réglementaire | RUO |
| Volume d’échantillon | Plasma: 100 μL, Serum: 100 μL |
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
| Cible | RNASE3 |
| Heure du test | 1 hr. 20 min. |
| Durée totale du dosage | 3 hr. 30 min. |
