"/> Tocris Bioscience™ PFI 7 | B-LABO France

Tocris Bioscience™ PFI 7

Réf. : BL-RE-178191Réf. fabricant : 30279877 10 mg
118,79 € HT

Selective GID4 antagonist

Nom chimique ou matériau
N-((1s,4s)-4-(1H-Benzo[d]imidazol-2-yl)cyclohexyl)-2-(((1H-indol-2-yl)methyl)amino)acetamide dihydrochloride
Quantité
10 mg
Cible
Ubiquitin Ligase (E3) Inhibitors
Formule moléculaire
C24H27N5O.2HCl
Pureté
0.98
Marque
Tocris Bioscience

PFI 7 is a selective GID4 antagonist (Kd = 80 nM by SPR assays and EC50 = 0.6 μM by cell-based NanoBRET). PFI 7 binds within the ?-barrel of GID4 substrate binding pocket, disrupting its interaction with the canonical Pro/N-degron peptide in live cells. It alters protein levels of several proteins including RNA helicases as measured by quantitative proteomics.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-178191
Réf. fabricant30279877
Nom chimique ou matériauN-((1s,4s)-4-(1H-Benzo[d]imidazol-2-yl)cyclohexyl)-2-(((1H-indol-2-yl)methyl)amino)acetamide dihydrochloride
Quantité10 mg
CibleUbiquitin Ligase (E3) Inhibitors
Formule moléculaireC24H27N5O.2HCl
Pureté0.98
Une question, une configuration particulière ?
Contactez-nous pour un devis.
Demander un devis 03 65 67 15 79

Produits similaires

Tocris Bioscience™ BAY 805

Tocris Bioscience™ BAY 805

174,94 € HT
Tocris Bioscience™ BAY 805

Tocris Bioscience™ BAY 805

174,94 € HT
Tocris Bioscience™ RNB 61

Tocris Bioscience™ RNB 61

236,49 € HT
Tocris Bioscience™ IBG3

Tocris Bioscience™ IBG3

231,10 € HT