Serum-free medium and supplement for the measurement of drug toxicity on megakaryocytes
Type de cellule
Hematopoietic Stem and Progenitor Cells, Megakaryocytes
À utiliser avec (application)
Cell Culture; Toxicity Assay
Quantité
1 Kit
Marque
STEMCELL Technologies
Caractéristiques principales
Screen large numbers of novel drug compounds for their effect on the proliferation and megakaryocyte-specific differentiation of human hematopoietic stem and progenitor cells (HSPCs)
Compared to using the colony forming unit (CFU) assay, the liquid culture-based HemaTox assay is more flexible: you can add test compounds at various points throughout the culture and measure their effects on more primitive or more mature progenitor cells
The HemaTox Megakaryocyte Kit promotes the proliferation of human CD34+ HSPCs and their differentiation into CD41-expressing megakaryocytes
Users can choose the readout method to quantify the response and estimate the IC50 and IC90 of each compound tested
Test up to 160 conditions in triplicate per kit in 5 x 96-well plates
This kit may be used on its own or in combination with HemaTox Erythroid Kit or HemaTox Myeloid Kit to assess lineage-specific drug toxicity in parallel
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-031867
Réf. fabricant
17121046
Type de cellule
Hematopoietic Stem and Progenitor Cells, Megakaryocytes
À utiliser avec (application)
Cell Culture; Toxicity Assay
Quantité
1 Kit
Une question, une configuration particulière ? Contactez-nous pour un devis.
