Tocris Bioscience™ Echistatin, alpha1 isoform
462,59 € HT
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
- Quantité
- 100 μg
- Marque
- Tocris Bioscience
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αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
Echistatin, α1 isoform is a potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM)
in vitro
.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-050304 |
| Réf. fabricant | 18016022 |
| Quantité | 100 μg |