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Tocris Bioscience™ Ispinesib

Name: Tocris Bioscience™ Ispinesib
Brand: Tocris Bioscience
SKU: 18700478
Price: 1418.97 EUR
Availability: InStock

Réf. : BL-RE-054881Réf. fabricant : 18700478 Ispinesib

1 418,97 € HT

High affinity and selective allosteric KSP inhibitor

Pureté: >98%
Description: Ispinesib
Poids moléculaire: 517.06
Type de produit: Ispinesib
Quantité: 50 mg
Marque: Tocris Bioscience

Ispinesib is a high affinity allosteric kinesin spindle protein (KSP) inhibitor (Ki app = 1.7 nM). Exhibits >10,000-fold selectivity for KSP over a range of other mitotic kinesins. Inhibits proliferation and induces apoptosis of prostate and breast cancer cells

in vitro

. Induces tumor regression of breast cancer cell xenografts in mice.