Potent and selective FPR2 agonist
MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 values are 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1β and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.
DMSO is not recommended as a solvent for this peptide.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-056439 |
| Réf. fabricant | 18084402 |
| Pureté | 0.95 |
| Poids moléculaire | 1610.97 |
| Type de produit | MMK 1 |
| Quantité | 1 mg |
| Séquence | Leu-Glu-Ser-Ile-Phe-Arg-Ser-Leu-Leu-Phe-Arg-Val-Met |
