Used for SDS-PAGE
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-056608 |
| Réf. fabricant | 16008096 |
| Concentration | 0.37 mg/mL |
| À utiliser avec (application) | SDS-PAGE |
| Formule | In 4mM sodium acetate, 0.15 M NaCl, pH 5.3 |
| Identification génétique (Entrez) | 2160 |
| Poids moléculaire | 80kDa |
| Nom | F11 (Human) Native Protein |
| Méthode de préparation | Native protein purified from human plasma |
| Méthode de purification | Multi-step chromatography |
| Quantité | 100 ug |
| Conditions de stockage | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | FXI/MGC141891 |
| Nom usuel | F11 |
| Symbole de gène(s) | F11 |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human plasma |
| Forme | Liquid |
| Pureté ou qualité | >98% by SDS-PAGE |
