Used for SDS-PAGE
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq]
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-056614 |
| Réf. fabricant | 16272100 |
| Numéro d’adhésion | P04114 |
| À utiliser avec (application) | SDS-PAGE |
| Formule | Lyophilized from 10mM sodium deoxycholate, 50mM Na |
| Identification génétique (Entrez) | 338 |
| Poids moléculaire | 550kDa |
| Nom | APOB (Human) Native Protein |
| Méthode de préparation | Native protein purified from human plasma |
| Quantité | 500 ug |
| Conditions de stockage | Store at -80°C on dry atmosphere. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | FLDB |
| Nom usuel | APOB |
| Symbole de gène(s) | APOB |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human plasma |
| Forme | Lyophilized |
| Pureté ou qualité | ≥90% by SDS-PAGE |
