STEMCELL Technologies HemaTox™ Erythroid Kit

Ref : 17199951
1645.50

Serum-free medium and supplement for the measurement of drug toxicity on erythroid cells

Type de cellule :
Hematopoietic Stem and Progenitor Cells, Erythroid Cells
À utiliser avec (application) :
Cell Culture; Toxicity Assay
Quantité :
1 Kit
Brand
STEMCELL Technologies

  • Screen large numbers of novel drug compounds for their effect on the proliferation and erythroid-specific differentiation of human hematopoietic stem and progenitor cells (HSPCs)
  • Compared to using the colony-forming unit (CFU) assay, the liquid culture-based HemaTox assay is more flexible: you can add test compounds at various points throughout the culture and measure their effects on more primitive or more mature progenitor cells
  • The HemaTox Erythroid Kit promotes the proliferation of CD34+ HSPCs and their differentiation into cells expressing erythroid markers such as CD71 and CD235a
  • Users can choose the readout method to quantify the response and estimate the IC50 and IC90 of each compound tested
  • Test up to 160 conditions in triplicate per kit in 5 x 96-well plates
  • This kit may be used on its own or in combination with HemaTox Myeloid Kit or HemaTox Megakaryocyte Kit to assess lineage-specific drug toxicity in parallel

Type de cellule : Hematopoietic Stem and Progenitor Cells, Erythroid Cells


À utiliser avec (application) : Cell Culture; Toxicity Assay


Quantité : 1 Kit