Potent MRGPRX1 agonist
BAM (8-22) is an endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM). It was first isolated from bovine adrenal medulla. Unlike BAM 22P (Cat. No. 1650), BAM (8-22) does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors. BAM (8-22) augments scratching behavior in a cholestatic pruritus mice model. BAM (8-22) attenuates bone cancer pain in mice.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-082581 |
| Réf. fabricant | 18797466 |
| Pureté | 0.95 |
| Nom usuel | Mas-Related G Protein Coupled Receptor Agonists |
| Contenu et stockage | Store at -20°C |
| Quantité | 1 mg |
