Endogenous agonist at OX1 and OX2
Orexin A (human, rat, mouse) is an endogenous agonist with high affinity at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Orexin A stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions. Orexin A impairs neurogenesis and hippocampal plasticity in mice. Orexin A improves glucose control and beta cell functions in type 2 diabetic animals.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-084227 |
| Réf. fabricant | 18748096 |
| Pureté | 0.95 |
| Contenu et stockage | Store at -20°C |
| Quantité | 500 μg |
