MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-091633 |
| Réf. fabricant | 18037454 |
| Numéro d’adhésion | P28862 |
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| Plage de dosage | 0.16 to 10 ng/mL |
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| Sensibilité du dosage | 0.1 ng/mL |
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| Conjugué | HRP |
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| Type de produit | ELISA |
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| Type d’échantillon | Plasma |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | 17392 |
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| Symbole de gène(s) | MMP3 |
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| Coefficient de variation inter-dosage | <10% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer |
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| Marqueur ou colorant | HRP |
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| Quantité | 96 Tests |
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| État réglementaire | RUO |
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| Volume d’échantillon | 100 µL |
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| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
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| Cible | Mouse |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 3 hr 30 min |
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