This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- Numéro d’adhésion
- Q99574
- Type de produit
- ELISA
- Identification génétique (Entrez)
- 5274
- Symbole de gène(s)
- Serpini1
- Quantité
- 10 x 96 Tests
- État réglementaire
- RUO
- Conditions de stockage
- Refer to product documentation for component specific storage temperature.
- Cible
- Human
