Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
Caractéristiques techniques
| Marque | Invitrogen |
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| Réf. B-LABO | BL-RE-092197 |
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| Réf. fabricant | 18597884 |
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| Numéro d’adhésion | 1110046O21Rik; AGP1; AGPT; Agpt1; Ang1; Ang-1; angiopoietin 1; angiopoietin-1; ANGPT1; endothelial growth factor; KIAA0003 |
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| Plage de dosage | 0.4 to 100 ng/mL |
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| Sensibilité du dosage | 0.4 ng/mL |
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| Conjugué | Biotin |
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| Type de produit | ELISA |
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| Type d’échantillon | Supernatant |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | O35460 |
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| Symbole de gène(s) | Angpt1 |
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| Coefficient de variation inter-dosage | <12% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | Research Use Only |
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| Volume d’échantillon | Plasma, 50 µL; Supernatant, 50 µL; Serum, 50 µL |
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| Conditions de stockage | 2°C to 8°C |
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| Cible | Angiopoietin 1 |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 4 hr 45 min |
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