FGFBP1 encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
Caractéristiques techniques
| Marque | Invitrogen |
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| Réf. B-LABO | BL-RE-093105 |
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| Réf. fabricant | 18527894 |
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| Numéro d’adhésion | 17 kDa HBGF-binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-binding protein 1; FGFBP; FGF-BP; Fgfbp1; FGF-BP1; FGFBP-1; fibroblast growth factor binding protein 1; fibroblast growth factor-binding protein 1; growth factor binding protein-1; growth factor-binding protein 1; HBP17; heparin-binding growth factor binding protein |
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| Plage de dosage | 0.41 to 100 ng/mL |
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| Sensibilité du dosage | 0.41 ng/mL |
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| Conjugué | Biotin |
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| Type de produit | ELISA |
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| Type d’échantillon | Serum |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | Q9QY10 |
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| Symbole de gène(s) | FGFBP1 |
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| Coefficient de variation inter-dosage | <12% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | Research Use Only |
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| Volume d’échantillon | Plasma, 50 µL; Supernatant, 50 µL; Serum, 50 µL |
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| Conditions de stockage | 2°C to 8°C |
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| Cible | FGFBP1 |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 4 hr 45 min |
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