This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
Caractéristiques techniques
| Marque | Invitrogen |
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| Réf. B-LABO | BL-RE-093113 |
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| Réf. fabricant | 18567844 |
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| Numéro d’adhésion | AA408458; Ags; AI325141; BA46; Breast epithelial antigen BA46; EDIL1; EGF/factor VIII; HMFG; hP47; HsT19888; lactadherin; Lactadherin short form; Medin; Mfge8; MFG-E8; MFGM; MFGME8; MFGMP-E8; milk fat globule glycoprotein; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; milk fat globule-EGF factor 8 protein; MP47; O-acetyl disialoganglioside synthase; O-acetyl GD3 ganglioside synthase; O-acetyltransferase milk fat globule membrane protein; O-acetyltransferase Milk fat glolbule membrane protein; OAcGD3S; P47; SED1; SPAG10; sperm associated antigen 10; sperm surface protein hP47; Sperm surface protein SP47 |
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| Plage de dosage | 0.1 to 25 ng/mL |
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| Sensibilité du dosage | 0.1 ng/mL |
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| Conjugué | Biotin |
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| Type de produit | ELISA |
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| Type d’échantillon | Supernatant |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | Q08431 |
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| Symbole de gène(s) | MFGE8 |
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| Coefficient de variation inter-dosage | <12% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
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| Marqueur ou colorant | HRP |
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| Quantité | 10 x 96 Tests |
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| État réglementaire | Research Use Only |
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| Volume d’échantillon | Supernatant, 50 µL; Serum, 50 µL; Plasma, 50 µL |
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| Conditions de stockage | 2°C to 8°C |
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| Cible | MFGE8 (Lactadherin) |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 4 hr 45 min |
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