Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
Caractéristiques techniques
| Marque | Invitrogen |
|---|
| Réf. B-LABO | BL-RE-093125 |
|---|
| Réf. fabricant | 18557804 |
|---|
| Numéro d’adhésion | 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; PCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor |
|---|
| Plage de dosage | 0.082 to 20 ng/mL |
|---|
| Sensibilité du dosage | 0.082 ng/mL |
|---|
| Conjugué | Biotin |
|---|
| Type de produit | ELISA |
|---|
| Type d’échantillon | Plasma |
|---|
| À utiliser avec (équipement) | Colorimetric Microplate Reader |
|---|
| Identification génétique (Entrez) | Q96IY4 |
|---|
| Symbole de gène(s) | CPB2 |
|---|
| Coefficient de variation inter-dosage | <12% |
|---|
| Coefficient de variation intra-dosage | <10% |
|---|
| Contenus des kits | Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers |
|---|
| Marqueur ou colorant | HRP |
|---|
| Quantité | 10 x 96 Tests |
|---|
| État réglementaire | Research Use Only |
|---|
| Volume d’échantillon | Serum, 50 µL; Plasma, 50 µL; Supernatant, 50 µL |
|---|
| Conditions de stockage | 2°C to 8°C |
|---|
| Cible | Carboxypeptidase B2 |
|---|
| Heure du test | 1 hr 20 min |
|---|
| Durée totale du dosage | 4 hr 45 min |
|---|
Une question, une configuration particulière ?
Contactez-nous pour un devis.
