The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-093665 |
| Réf. fabricant | 18067364 |
| Numéro d’adhésion | P43235 |
|---|
| Plage de dosage | 0.16 to 10 ng/mL |
|---|
| Sensibilité du dosage | 0.1 ng/mL |
|---|
| Conjugué | HRP |
|---|
| Type de produit | ELISA |
|---|
| Type d’échantillon | Plasma |
|---|
| À utiliser avec (équipement) | Colorimetric Microplate Reader |
|---|
| Identification génétique (Entrez) | 1513 |
|---|
| Symbole de gène(s) | CTSK |
|---|
| Coefficient de variation inter-dosage | <10% |
|---|
| Coefficient de variation intra-dosage | <10% |
|---|
| Contenus des kits | Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer |
|---|
| Marqueur ou colorant | HRP |
|---|
| Quantité | 96 Tests |
|---|
| État réglementaire | RUO |
|---|
| Volume d’échantillon | 100 µL |
|---|
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
|---|
| Cible | Human |
|---|
| Heure du test | 1 hr 20 min |
|---|
| Durée totale du dosage | 3 hr 30 min |
Une question, une configuration particulière ?
Contactez-nous pour un devis.