Cx43 hemichannel blocker
TAT-Gap19 is a Cx43 hemichannel blocker (IC50 ~7 μM). No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19 (Cat. No. 5353). Active
in vivo
. Brain penetrant.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-103966 |
| Réf. fabricant | 18719967 |
| Pureté | 95% |
| CAS | 1507930-54-2 |
| Contenu et stockage | Store at −20°C |
| Poids moléculaire | 2703.28g/mol |
| Quantité | 1 mg |
| État réglementaire | RUO - research use only |
| Séquence | YGRKKRRQRRRKQIEIKKFK |
| Réactivité spécifique | Cx43 hemichannel blocker (IC50=7μM) |
