H-7 dihydrochloride is a protein kinase inhibitor (IC50 values for inhibition of PKA, PKG, PKC and myosin light chain kinase are 3.0, 5.8, 6.0 and 97.0 μM, respectively. H-7 shows antiviral activity against influenza A (IC50 = 10 μM) in vitro. H-7 also inhibits interleukin-stimulated secretion of IgM and blocks PMA -stimulated interleukin 1β production.
- Nom chimique ou matériau
- '±-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride
- CAS
- 108930-17-2
- Plage de pourcentage du dosage
- >99%
- Quantité
- 50 mg
- Solubilité
- Soluble to 20mM in DMSO
- Formule moléculaire
- C14H17N3O2S.2HCl
- Poids de la formule
- Observed MW: 364.29