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STEMCELL Technologies SB431542 (Hydrate) | B-LABO France
STEMCELL Technologies SB431542 (Hydrate)
Réf. : BL-RE-126392Réf. fabricant : 17199241 1 mg
89,10 € HT
Activin/BMP/TGFβ pathway inhibitor; Inhibits ALK4, ALK5, and ALK7
Synonyme
SB-431542
Quantité
1 mg
Formule moléculaire
C22H16N4O3 · XH2O
Pureté
≥98%
Marque
STEMCELL Technologies
Caractéristiques principales
SB431542 is a selective and potent inhibitor of the TGF-β/Activin/NODAL pathway that inhibits ALK5 (IC50 = 94 nM), ALK4 (IC50 = 140 nM), and ALK7 by competing for the ATP binding site
It does not inhibit the BMP type I receptors ALK2, ALK3, and ALK6
This product is supplied as the hydrate form of the molecule
