BI-D1870 inhibits the 90 kDa ribosomal S6 kinases (RSKs), which are serine/threonine kinases involved in diverse cellular processes including growth, survival, and motility (Romeo et al.)
Reduces neural stem cell proliferation and self-renewal in vitro (Karelina et al.)
Inhibits growth of breast cancer cell lines (Stratford et al.), Dhillon et al.)