Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)
CAS
320-67-2
Synonyme
5-AzaC; Antibiotic U 18496; Ladakamycin; Mylosar; NSC 103-627; NSC 102816; U 18496; WR 183027; Zcyd
Quantité
250 mg
Formule moléculaire
C8H12N4O5
Pureté
≥95%
Marque
STEMCELL Technologies
Caractéristiques principales
5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA
5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity
Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.)
Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.)
Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.)
Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126509
Réf. fabricant
17140012
CAS
320-67-2
Synonyme
5-AzaC; Antibiotic U 18496; Ladakamycin; Mylosar; NSC 103-627; NSC 102816; U 18496; WR 183027; Zcyd
