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STEMCELL Technologies Sodium Butyrate

Réf. : BL-RE-126554Réf. fabricant : 17180042 500 mg
95,85 € HT

Epigenetic modifier; Inhibits histone deacetylase

CAS
156-54-7
Synonyme
Butanoic acid; Butyric acid, sodium salt
Quantité
500 mg
Formule moléculaire
C4H7O2 · Na
Pureté
≥95%
Marque
STEMCELL Technologies

Caractéristiques principales

  • Sodium Butyrate is the sodium salt of butyric acid, a short chain fatty acid that inhibits histone deacetylases (HDACs), leading to hyperacetylation of histones
  • This causes changes in chromatin structure and gene expression, resulting in many biological effects
  • (Boffa et al.; Kruh)
  • Promotes reprogramming of human somatic cells to induced pluripotent stem (iPS) cells using only a single factor, OCT4 (Zhu et al.)
  • Supports self-renewal of mouse and human embryonic stem (ES) cells, in the absence of exogenously added growth factors (Ware et al.)
  • Promotes differentiation to hepatocytes from mouse and human ES cells (Hay et al.; Zhou et al.)
  • Promotes differentiation to definitive endoderm and islet-like cells from human ES cells (Jiang et al.)
  • Enhances osteogenic and suppresses adipogenic differentiation from human mesenchymal cells (Chen et al.; Lee et al.)

Caractéristiques techniques

MarqueSTEMCELL Technologies
Réf. B-LABOBL-RE-126554
Réf. fabricant17180042
CAS156-54-7
SynonymeButanoic acid; Butyric acid, sodium salt
Quantité500 mg
Formule moléculaireC<sub>4</sub>H<sub>7</sub>O<sub>2</sub> · Na
Pureté≥95%
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