Caractéristiques principales
- LY294002 is a PI3K inhibitor that has greater potency and selectivity than quercetin, the structure on which it is based
- LY294002 inhibits PI3K (IC50 = 1.4 μM) and also shows activity against CK2, but not PI4K, EGFR, PDGFR, MAPK, PKA, or PKC
- (Davies et al.), Vlahos et al.)
- Suppresses proliferation and self-renewal of mouse embryonic stem (ES) cells (Lianguzova et al.), Paling et al.)
- Promotes differentiation to insulin-producing cells from mouse ES cells (Hori et al.)
- Inhibits myotube formation from myoblasts (Coolican et al.), Jiang et al.)
Caractéristiques techniques
| Marque | STEMCELL Technologies |
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| Réf. B-LABO | BL-RE-126621 |
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| Réf. fabricant | 17150032 |
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| CAS | 154447-36-6 |
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| Quantité | 25 mg |
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| Formule moléculaire | C<sub>19</sub>H<sub>17</sub>NO<sub>3</sub> |
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| Pureté | ≥98% |
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