Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)
CAS
1418131-46-0
Quantité
10 mg
Formule moléculaire
C18H15N3O2
Pureté
≥95%
Marque
STEMCELL Technologies
Caractéristiques principales
Reprogramming stimulating compound (RSC)-133 is an indole derivative that specifically inhibits DNA methyltransferase DNMT1 (Lee et al.)
Increases kinetics and efficiency of reprogramming human foreskin fibroblasts to induced pluripotent stem cells, when used with reprogramming factors OCT4, SOX2, KLF4, and c-MYC (Lee et al.)
Supports the maintenance of human pluripotent stem cells in unconditioned medium (Lee et al.)