Raloxifene is a selective estrogen receptor modulator (SERM) that exhibits agonistic (estrogenic) activity in bone cells without stimulating ER activity in breast or uterine tissues (Black et al.)
Enhances osteoblast differentiation in mouse bone marrow and human osteoblast cultures (Qu et al.; Viereck et al.)
Inhibits osteoclast differentiation in primary human bone marrow mononuclear cell cultures (Ramalho et al.)
Reduced endodermal differentiation (HNF-4α expression) in embryoid bodies derived from human embryonic stem (ES) cells (Kim et al.)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126658
Réf. fabricant
17180132
CAS
82640-04-8
Synonyme
Evista™; Keoxifene; LY156758
Quantité
500 mg
Formule moléculaire
C<sub>28</sub>H<sub>27</sub>NO<sub>4</sub>S · HCl
Pureté
≥98%
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