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STEMCELL Technologies Quercetin (Hydrate) | B-LABO France
STEMCELL Technologies Quercetin (Hydrate)
Réf. : BL-RE-126661Réf. fabricant : 17180292 10 g
52,65 € HT
mTOR, PI3K/AKT, NF-kB, and tyrosine kinase pathway inhibitor; Inhibits PI3K and SRC kinases
CAS
849061-97-8
Quantité
10 g
Formule moléculaire
C15H10O7 · XH2O
Pureté
≥95%
Marque
STEMCELL Technologies
Caractéristiques principales
Quercetin inhibits phosphoinositide 3-kinase isoforms (beta: IC50 = 5.4 μM; gamma: IC50 = 2.4 μM; delta: IC50 = 3.0 μM) and SRC kinases but only shows slight inhibitory activity against serine/threonine kinases ERK1/2 and p38 alpha, as well as protein kinase C (Navarro-Nunez et al.)
Stimulates glycolytic metabolism and promotes reprogramming of somatic cells (Zhang et al.)
Enhances reprogramming of human primary somatic cells to induced pluripotent stem cells (Zhu et al.)
Induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation (Triantafyllou et al.)
Promotes apoptosis of glioblastoma cells when used together with temozolomide (Sang et al.)
Reduces tumorigenicity of pancreatic cancer cells (Fan et al.)
