"/> STEMCELL Technologies WHI-P154 | B-LABO France

STEMCELL Technologies WHI-P154

Réf. : BL-RE-126717Réf. fabricant : 17150242 10 mg
168,75 € HT

JAK/STAT pathway inhibitor; Inhibits JAK3

CAS
211555-04-3
Synonyme
JAK3 Inhibitor II; Janus-Associated Kinase 3 Inhibitor II
Quantité
10 mg
Formule moléculaire
C16H14BrN3O3
Pureté
≥98%
Marque
STEMCELL Technologies

Caractéristiques principales

  • WHI-P154 is an inhibitor of Janus kinase 3 (JAK3) with IC50 values of 28 and 128 μM against human and mouse proteins, respectively (Sudbeck et al.) It has also been reported to show significant inhibition of other kinases, including epidermal growth factor receptor (EGFR) in the nanomolar range (Changelian et al.; Uckun et al.) No significant inhibition of JAK1 or JAK2 has been observed (Sudbeck et al.)

Caractéristiques techniques

MarqueSTEMCELL Technologies
Réf. B-LABOBL-RE-126717
Réf. fabricant17150242
CAS211555-04-3
SynonymeJAK3 Inhibitor II; Janus-Associated Kinase 3 Inhibitor II
Quantité10 mg
Formule moléculaireC<sub>16</sub>H<sub>14</sub>BrN<sub>3</sub>O<sub>3</sub>
Pureté≥98%
Une question, une configuration particulière ?
Contactez-nous pour un devis.