JAK3 Inhibitor II; Janus-Associated Kinase 3 Inhibitor II
Quantité
10 mg
Formule moléculaire
C16H14BrN3O3
Pureté
≥98%
Marque
STEMCELL Technologies
Caractéristiques principales
WHI-P154 is an inhibitor of Janus kinase 3 (JAK3) with IC50 values of 28 and 128 μM against human and mouse proteins, respectively (Sudbeck et al.) It has also been reported to show significant inhibition of other kinases, including epidermal growth factor receptor (EGFR) in the nanomolar range (Changelian et al.; Uckun et al.) No significant inhibition of JAK1 or JAK2 has been observed (Sudbeck et al.)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126717
Réf. fabricant
17150242
CAS
211555-04-3
Synonyme
JAK3 Inhibitor II; Janus-Associated Kinase 3 Inhibitor II